You will find there's launch of norepinephrine from the descending inhibitory bulbospinal neurons that binds to alpha-2-receptors inside the dorsal horn to reduce afferent discomfort transmission and create analgesia. For that reason, medications like clonidine that focus on alpha-2 receptors can impact the transmission of pain. : connected to, https://expressbookmark.com/story19754133/not-known-factual-statements-about-onolidine