Opioid-induced infant deaths have occurred from breastfeeding by mothers who ended up ultrarapid metabolizers having codeine postpartum. Conversely, weak metabolizers may possibly experience lousy pain relief when treated with codeine. The presence of the methyl team over the number 3 carbon restrictions the first-go presystemic metabolism of codeine during the https://topdirectory1.com/listings13190355/an-unbiased-view-of-codeine-to-morphine-bnf