There exists a launch of norepinephrine from the descending inhibitory bulbospinal neurons that binds to alpha-two-receptors in the dorsal horn to lessen afferent pain transmission and develop analgesia. Consequently, medicines like clonidine that concentrate on alpha-2 receptors can impact the transmission of pain. Applies to clonidine: oral pill, oral https://carli036khd6.daneblogger.com/profile