In older clients, This is often essential to comprehend as polypharmacy is common and can potentiate the risk of DDIs and ADRs. Hence, concurrent ingestion of CYP2D6 inhibitors or inducers could potentiate or block tramadol conversion into ODT and This might boost or minimize efficacy/ADRs in the prescribed tramadol. https://hemalchem.com/product/o-dsmt/